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Research article

Intrathecal ropivacaine vs bupivacaine in endoscopic urological surgeries: a double blind randomized controlled trial

Authors:

Abhishek Rao Kordcal,

Manipal Academy of Higher Education, Manipal, IN
About Abhishek Rao
Assistant Professor, Department of Anaesthesiology, Kasturba Medical College
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Vijaykumar Tipanna Kalyanappagol,

Shri BM Patil Medical College, Bijapur, IN
About Vijaykumar Tipanna
Professor, Department of Anaesthesiology
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Amrut Krishnananda Rao ,

Manipal Academy of Higher Education, Manipal, IN
About Amrut Krishnananda
Assistant Professor, Department of Anaesthesiology, Kasturba Medical College
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Madhu Rao

Manipal Academy of Higher Education, Manipal, IN
About Madhu
Assistant Professor, Department of Anaesthesiology, Kasturba Medical College
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Abstract

Aims: To compare sensory, motor effects and haemodynamic stability of 2ml intrathecal isobaric ropivacaine (0.75%) with 3ml hyperbaric bupivacaine (0.75%) in patients undergoing endoscopic urological surgery.

 

Study Design: Randomized controlled trial involving 142 patients undergoing transurethral resection of prostate (TURP) and URS (urethroscopy) in a tertiary care hospital, India.

 

Methods and materials: Patients were randomly allocated to, Group 1 (3ml of 0.5% (15mg) hyperbaric bupivacaine) and Group 2 (2ml of 0.75% isobaric ropivacaine(15mg)). Onset and highest level of sensory block, onset and duration of motor block, quality of anaesthesia and muscle relaxation, haemodynamic parameters and adverse effects if any were studied. Statistical analysis used: Unpaired t-test was used to test continuous variables and chi square test/Fisher’s exact test for categorical variables.

 

Results: The mean of highest sensory block, 2 segment regression of sensory block and time for sensory level to regress below T10 was significantly more in group 1 compared to group 2 (P<0.05). There was a significant delay of mean time to onset of motor block to Bromage score 1 in group 2(P<0.001). The mean duration of complete motor blockade was significantly more in group 1 (P value <0.001). Hypotension was most commonly seen in group 1.

 

Conclusion: Ropivacaine provides comparable quality of sensory block but has slower onset and significantly shorter duration of motor block compared to hyperbaric bupivacaine.
How to Cite: Kordcal, A.R., Kalyanappagol, V.T., Rao, A.K. and Rao, M., 2019. Intrathecal ropivacaine vs bupivacaine in endoscopic urological surgeries: a double blind randomized controlled trial. Sri Lankan Journal of Anaesthesiology, 27(2), pp.127–132. DOI: http://doi.org/10.4038/slja.v27i2.8414
Published on 16 Jul 2019.
Peer Reviewed

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