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Clinical Investigations

Comparison of different doses of Fentanyl for prevention of hemodynamic changes during induction and intubation in parturients undergoing caesarian section under general anesthesia.

Authors:

Shrikrishna Govind Deogaonkar ,

Pravara Institute of Medical Sciences, Loni 413736, IN
About Shrikrishna
Associate Professor, Department of Anaesthesiology and Critical Care, Pravara Institute of Medical Sciences, Loni 413736
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Jagannath Lakhe,

Pravara Institute of Medical Sciences, Loni 413736, IN
About Jagannath
Professor, Department of Anaesthesiology and Critical Care, Pravara Institute of Medical Sciences, Loni 413736
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Bhavika Singla,

Pravara Institute of Medical Sciences, Loni 413736, IN
About Bhavika
Senior Resident, Department of Anaesthesiology and Critical Care, Pravara Institute of Medical Sciences, Loni 413736
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Ramchandra Vinayak Shidhaye

L.N.Medical College and J.K. Hospital, Kolar Road Bhopal 462042, IN
About Ramchandra
Professor, Department of Anaesthesiology and Critical Care L.N.Medical College and J.K. Hospital, Kolar Road Bhopal 462042
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Abstract

Introduction: Present study was designed to find low, safe and efficacious dose of fentanyl to avoid its foetal side effects by comparing two doses of fentanyl to prevent haemodynamic hazards at induction and intubation in patients undergoing caesarean section (CS) under general anaesthesia (GA).

Method: Forty five full term parturients posted for emergency/elective caesarean section under GA of ASA Grade I or II, age group between 18 to 35 years were randomly distributed into three groups. Intravenous fentanyl 0.5µg/kg or1µg/kg diluted to 5 ml or normal saline 5 ml was administered three minutes before induction in Group F 0.5, Group F1or Group C respectively. Maternal haemodynamic parameters and foetal parameters were recorded at different time intervals.

Results: Group F and Group F1 showed significant reduction and stability in maternal haemodynamics when compared with the control group, but no statistical difference was observed amongst them. No difference was observed in foetal Apgar score and cord blood pH in all three groups.

Conclusion: Fentanyl in doses as low as 0.5µg/kg can be used safely in parturients to prevent haemodynamic hazards at intubation in patients undergoing CS under GA.

How to Cite: Deogaonkar, S.G. et al., (2016). Comparison of different doses of Fentanyl for prevention of hemodynamic changes during induction and intubation in parturients undergoing caesarian section under general anesthesia.. Sri Lankan Journal of Anaesthesiology. 24(1), pp.28–31. DOI: http://doi.org/10.4038/slja.v24i1.8121
Published on 11 Feb 2016.
Peer Reviewed

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