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Reading: Anaesthetic management of a case of Alkaptonuria for Total knee arthroplasty.

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Case Reports

Anaesthetic management of a case of Alkaptonuria for Total knee arthroplasty.

Authors:

Anbarasan Ardhanari ,

IN
About Anbarasan

Senior Registrar

Department of Anaesthesiology & Pain Relief

Apollo Speciality Hospital, Bengaluru, Karnataka

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Vinaya Kumar V Seetharam,

IN
About Vinaya Kumar

Consultant

Department of Anaesthesiology & Pain Relief

Apollo Speciality Hospital, Bengaluru, Karnataka
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Muralidhar Thondebhavi Subbaramaiah,

IN
About Muralidhar

Consultant

Department of Anaesthesiology & Pain Relief

Apollo Speciality Hospital, Bengaluru, Karnataka
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MS Kumaraswamy

IN
About MS

Senior Consultant

Department of Anaesthesiology & Pain Relief

Apollo Speciality Hospital, Bengaluru, Karnataka
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Abstract

Alkaptonuria, is a rare autosomal recessive disorder of tyrosine metabolism caused by a deficiency of homogentisate 1,2dioxygenase. It results in accumulation of homogentisic acid in spine and large joints and cardiac valves. It also involves respiratory, airway, genitourinary, cutaneous and ocular systems.  Administering spinal anaesthesia is extremely challenging in these cases. We report a case of a 66yr old male alkaptonuric ochronosis with symptoms of ankylosing spondylitis, hypertension and obstructive sleep apnoea for total knee replacement successfully managed intraoperatively with subarachnoid block after marking the interspinous space with ultrasound.

DOI: http://dx.doi.org/10.4038/slja.v23i1.7751

How to Cite: Ardhanari, A. et al., (2015). Anaesthetic management of a case of Alkaptonuria for Total knee arthroplasty.. Sri Lankan Journal of Anaesthesiology. 23(1), pp.32–34. DOI: http://doi.org/10.4038/slja.v23i1.7751
Published on 11 Jan 2015.
Peer Reviewed

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