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Clinical Investigations

Renal function in patients undergoing cardiopulmonary bypass for open cardiac surgical procedures

Authors:

Irshad Ahmad Shiekh,

IN
About Irshad

Assistant Professor,Anaesthesiology and Critical Care,Sher-i-Kashmir Institute of Medical Sciences,Srinagar

 

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Mubasher Ahmad Bhat ,

IN
About Mubasher
Senior Resident, Anaesthesiology and critical care,  Sher-i-Kashmir Institute of Medical Sciences, Srinagar.
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Abdul Wahid Bhat,

IN
About Abdul

Assistant Professor, Blood Transfusion and Immunohaematology, Sher-i-Kashmir Institute of Medical Science, Srinagar

 

 

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Mohamad Ommid,

IN
About Mohamad

Lecturer, Anaesthesiology, Government Medical College, Srinagar,

 

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Tanveera Gani,

IN
About Tanveera

Assistant Surgeon, Health and Medical Education, Department of Health services, Jammu and Kashmir

 

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Gousia Nisa

IN
About Gousia

Assistant Surgeon, Health and Medical Education, Department of Health services, Jammu and Kashmir

 

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Abstract

Background:

Renal dysfunction following cardiopulmonary bypass is a frequent complication of open heart surgery. Acute renal failure requiring dialysis occurs in approximately 1.5% of patients following cardiac surgery and remains a cause of major morbidity and mortality.

Method:

Sixty-five patients of either sex in the age group of 10 – 50 years scheduled to undergo various cardiac procedures were included in this study. All patients had normal preoperative levels of serum creatinine, blood urea nitrogen, blood glucose levels, urine analysis, 24 hour urinary protein < 200 mg, and normal 24 hour creatinine clearance. After surgery, patients were transferred to an intensive care unit for postoperative management and monitoring. Patients were shifted to cardiovascular and thoracic surgery ward as soon as their clinical condition permitted. Blood urea nitrogen, serum creatinine, 24 hour creatinine clearance was performed on day one and day seven of postoperative period.

Result:

Postoperative oliguric acute renal failure was 7.7% and overall mortality was 6.1%. We found no association between aortic cross clamp time and postoperative renal dysfunction.

Conclusion:

Optimisation of cardiac performance post cardiopulmonary bypass seems to be the most important factor in the prevention of postoperative renal dysfunction in patients requiring total cardiopulmonary bypass.

DOI: http://dx.doi.org/10.4038/slja.v21i1.4544

How to Cite: Shiekh, I.A. et al., (2013). Renal function in patients undergoing cardiopulmonary bypass for open cardiac surgical procedures. Sri Lankan Journal of Anaesthesiology. 21(1), pp.20–26. DOI: http://doi.org/10.4038/slja.v21i1.4544
Published on 22 Feb 2013.
Peer Reviewed

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