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Profound central depression during treatment of tetanus with combined magnesium, midazolam, morphine and fentanyl

Authors:

RMMKN Rathnayaka ,

LK
About RMMKN
Trainee in Medical Toxicology, Medical Officer - Intensive care unit, Provincial General Hospital,Ratnapura
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Janaka Ranaweera,

LK
About Janaka
Consultant Anaesthetist, Provincial General Hospital, Ratnapura
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P Palihakkara,

LK
About P
Consultant Anaesthetist, Provincial General Hospital, Ratnapura
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PEAN Ranathunga

LK
About PEAN
Medical Officer,Emergency treatment unit,Provincial General Hospital, Ratnapura
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Abstract

A 61year old male patient with generalized tetanus developed central depression due to combined use of magnesium sulphate, midazolam, morphine and fentanyl. He was successfully treated with magnesium sulphate (MgSO4) infusion with the minimal usage of sedatives and paralytic agents. Lowering of GCS occurred on day 6, 7 and 8 indicating central depression.
DOI: http://doi.org/10.4038/slja.v23i2.8077
How to Cite: Rathnayaka, R. et al., (2015). Profound central depression during treatment of tetanus with combined magnesium, midazolam, morphine and fentanyl. Sri Lankan Journal of Anaesthesiology. 23(2), pp.86–88. DOI: http://doi.org/10.4038/slja.v23i2.8077
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Published on 22 Jul 2015.
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